Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.76 |
| ▸ | NPC1 | O15118 | 4/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | MITF | O75030 | 1/20 | 0.60 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | ALPI | P09923 | 1/20 | 0.58 |
| ▸ | KDR | P35968 | 1/20 | 0.58 |
| ▸ | SNCA | P37840 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL641989 | 0.89 | PHGDH (0.77) | PHGDHNPC1ALDH1A1MAPTPOLB | |
| SCHEMBL27864285 | 0.88 | PHGDH (0.61) | PHGDHNPC1ALDH1A1MAPTPOLB | |
| SCHEMBL28851799 | 0.87 | NPC1 (0.63) | PHGDHNPC1ALDH1A1MAPTPOLB | |
| SCHEMBL27847056 | 0.86 | PHGDH (0.74) | PHGDHNPC1ALDH1A1MAPTPOLB | |
| SCHEMBL8337442 | 0.86 | NPC1 (0.80) | NPC1ALDH1A1MAPTPOLBRAB9A | |
| SCHEMBL23673663 | 0.84 | NPC1 (0.73) | NPC1ALDH1A1MAPTPOLBRAB9A | |
| SCHEMBL28734353 | 0.84 | NPC1 (1.00) | NPC1ALDH1A1MAPTPOLBRAB9A | |
| SCHEMBL11189491 | 0.84 | HCAR3 (0.65) | PHGDHNPC1ALDH1A1MAPTPOLB | |
| SCHEMBL10376329 | 0.84 | PHGDH (0.70) | PHGDHNPC1ALDH1A1MAPTPOLB | |
| SCHEMBL6169544 | 0.84 | NPC1 (0.78) | PHGDHNPC1ALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |
| US-4933368-A | FOR ADMINISTERING TO REAT REFRACTORY TUMORS IN MAMMALS | GODECKE AKTIENGESELLSCHAFT (DE) | 1990-06-12 | — | — | US | disclosed |
| EP-0116967-B1 | N-PHENYL-BENZAMIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1986-01-29 | — | — | EP | disclosed |
| EP-0116967-A1 | N-phenyl-benzamide derivatives, process for their preparation and medicines containing them | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1984-08-29 | — | — | EP | disclosed |