Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955513 | 0.94 | NPSR1 (0.36) | MAPTNPSR1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL6958506 | 0.91 | SMN1; SMN2 (0.39) | MAPTNPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6962207 | 0.90 | SMN1; SMN2 (0.38) | NPSR1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL6961412 | 0.90 | SMN1; SMN2 (0.37) | MAPTNPSR1HTTSMN1; SMN2KMT2A | |
| SCHEMBL6957959 | 0.89 | SMN1; SMN2 (0.38) | MAPTNPSR1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL6964622 | 0.88 | SMN1; SMN2 (0.37) | NPSR1SMN1; SMN2 | |
| SCHEMBL6957189 | 0.88 | SMN1; SMN2 (0.37) | MAPTNPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6959003 | 0.88 | TP53 (0.41) | MAPTNPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6958365 | 0.87 | MAPT (0.38) | MAPTNPSR1SMN1; SMN2KMT2ATP53 | |
| SCHEMBL6961241 | 0.87 | HTR2A (0.36) | MAPTNPSR1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | claimed |
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |