Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPEP | Q07075 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | BBOX1 | O75936 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18008285 | 0.94 | ENPEP (0.48) | ENPEPKDM4EMAPTALOX15BBOX1 | |
| Potassium Ion SCHEMBL18008001 | 0.94 | ENPEP (0.43) | ENPEPKDM4EMAPTALOX15BBOX1 | |
| Lithium Ion SCHEMBL18008794 | 0.94 | ENPEP (0.43) | ENPEPKDM4EMAPTALOX15BBOX1 | |
| SCHEMBL7582594 | 0.94 | ENPEP (0.43) | ENPEPKDM4EMAPTALOX15BBOX1 | |
| Tetrylammonium SCHEMBL18008216 | 0.84 | BBOX1 (0.41) | ENPEPKDM4EMAPTALOX15BBOX1 | |
| SCHEMBL966470 | 0.79 | ENPEP (0.52) | ENPEPKDM4EMAPTALOX15BBOX1 | |
| Potassium Ion SCHEMBL18008837 | 0.79 | ENPEP (0.47) | ENPEPKDM4EMAPTALOX15BBOX1 | |
| Lithium Ion SCHEMBL18008417 | 0.79 | ENPEP (0.47) | ENPEPKDM4EMAPTALOX15BBOX1 | |
| Potassium Ion SCHEMBL18008684 | 0.77 | BBOX1 (0.43) | ENPEPKDM4EMAPTALOX15BBOX1 | |
| Lithium Ion SCHEMBL18007911 | 0.77 | BBOX1 (0.43) | ENPEPKDM4EMAPTALOX15BBOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0974582-B1 | Process for the preparation of 4-substituted azetidinone derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 2003-02-12 | — | — | EP | claimed |