Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6956223 | 0.89 | MAPT (0.49) | KMT2AMEN1ALOX5NPC1RAB9A | |
| SCHEMBL8891824 | 0.86 | MAPT (0.54) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6952697 | 0.85 | MAPT (0.48) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6963996 | 0.85 | MEN1 (0.50) | KMT2AMEN1GAAALOX5NPC1 | |
| SCHEMBL6955042 | 0.85 | ALOX5 (0.51) | KMT2AMEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL6955473 | 0.84 | ALOX5 (0.46) | KMT2AMEN1ALOX5NPC1RAB9A | |
| SCHEMBL6962415 | 0.83 | MTNR1A (0.50) | KMT2AMEN1ALOX5NPC1RAB9A | |
| SCHEMBL6963453 | 0.83 | ALOX5 (0.49) | KMT2AMEN1GAAALOX5NPC1 | |
| SCHEMBL6964076 | 0.81 | ALOX5 (0.49) | KMT2AALOX5NPC1RAB9AALDH1A1 | |
| SCHEMBL6958388 | 0.81 | ALOX5 (0.51) | KMT2AMEN1GAACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540143-B1 | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 2003-02-05 | — | — | EP | disclosed |
| US-5714503-A | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 1998-02-03 | — | — | US | disclosed |
| US-5593993-A | VIRICIDES FOR HTLV TREATMENT OF AIDS | MEDIVIR AB (SE) | 1997-01-14 | — | — | US | disclosed |
| EP-0540143-A2 | Compounds and methods for inhibition of HIV and related viruses | Medivir Aktiebolag (SE) | 1993-05-05 | — | — | EP | disclosed |