SCHEMBL6959452

SCHEMBL6959452

CC(C)(C)OC(=O)ON1CCC(c2ccc(OCCCOCc3ccccc3)cc2)C(OCc2ccc3c(c2)NCCC3)C1

nearest known ligand 0.65

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7081006 0.92 REN (0.52) REN
SCHEMBL6958042 0.91 REN (0.69) REN
SCHEMBL4603776 0.91 REN (0.69) REN
SCHEMBL6954895 0.88 REN (0.52) REN
SCHEMBL6956250 0.88 REN (0.47) REN
SCHEMBL7075548 0.86 REN (0.58) REN
SCHEMBL6042803 0.86 REN (0.73) REN
SCHEMBL6951729 0.86 REN (0.46) REN
SCHEMBL7082632 0.86 REN (0.46) REN
SCHEMBL7080739 0.85 REN (0.53) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0863875-B1 NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY HOFFMANN LA ROCHE (CH) 2003-06-04 EP disclosed