Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6958042 | 1.00 | REN (0.69) | RENCYP3A4ACHE | |
| SCHEMBL6959452 | 0.91 | REN (0.65) | REN | |
| SCHEMBL4603206 | 0.91 | REN (0.70) | RENCYP3A4ACHE | |
| SCHEMBL5561550 | 0.91 | REN (0.70) | RENCYP3A4ACHE | |
| SCHEMBL6043442 | 0.87 | REN (0.74) | RENCYP3A4 | |
| SCHEMBL6952773 | 0.86 | REN (0.55) | REN | |
| SCHEMBL7085119 | 0.85 | REN (0.58) | REN | |
| SCHEMBL6948724 | 0.85 | REN (0.66) | REN | |
| SCHEMBL4603519 | 0.85 | REN (0.66) | REN | |
| SCHEMBL6949184 | 0.85 | REN (0.67) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979819-B1 | Process for the production of substituted 3-hydroxypiperidines | SPEEDEL PHARMA AG (CH) | 2008-04-23 | — | — | EP | claimed |