Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CDC25B | P30305 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.46 |
| ▸ | CDC25C | P30307 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13032652 | 0.86 | TSHR (0.67) | TSHRALDH1A1HSD17B10L3MBTL1CDC25B | |
| SCHEMBL1898535 | 0.86 | TSHR (0.67) | TSHRALDH1A1HSD17B10L3MBTL1CDC25B | |
| SCHEMBL1492385 | 0.86 | TSHR (0.67) | TSHRALDH1A1HSD17B10L3MBTL1CDC25B | |
| SCHEMBL578128 | 0.85 | TSHR (0.77) | TSHRALDH1A1HSD17B10L3MBTL1CDC25B | |
| SCHEMBL1492404 | 0.85 | TSHR (0.65) | TSHRALDH1A1HSD17B10L3MBTL1CDC25B | |
| SCHEMBL6441720 | 0.83 | TSHR (0.67) | TSHRALDH1A1HSD17B10CDC25BKDM4E | |
| SCHEMBL6959625 | 0.82 | ALDH1A1 (0.65) | TSHRALDH1A1HSD17B10KDM4EKMT2A | |
| SCHEMBL7670783 | 0.82 | TSHR (0.71) | TSHRALDH1A1HSD17B10L3MBTL1CDC25B | |
| SCHEMBL7669334 | 0.82 | TSHR (0.71) | TSHRALDH1A1HSD17B10L3MBTL1CDC25B | |
| Bicarbonate SCHEMBL27963013 | 0.81 | TSHR (0.65) | TSHRALDH1A1HSD17B10L3MBTL1CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |