Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | IL1RN | P18510 | 1/20 | 0.51 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.51 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 4/20 | 0.49 |
| ▸ | CTSK | P43235 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12516497 | 0.87 | ERAP2 (0.57) | ALDH1A1IL1RNERAP2ERAP1CTSB | |
| SCHEMBL8707008 | 0.85 | ALDH1A1 (0.53) | ALDH1A1IL1RNERAP2ERAP1CTSB | |
| SCHEMBL6959620 | 0.85 | ALDH1A1 (0.53) | ALDH1A1IL1RNERAP2ERAP1CTSB | |
| SCHEMBL8228565 | 0.85 | ALDH1A1 (0.53) | ALDH1A1IL1RNERAP2ERAP1CTSB | |
| Hydrochloric Acid SCHEMBL25265036 | 0.84 | ALDH1A1 (0.51) | ALDH1A1IL1RNERAP2ERAP1CTSB | |
| Hydrochloric Acid SCHEMBL8712756 | 0.84 | ALDH1A1 (0.51) | ALDH1A1IL1RNERAP2ERAP1CTSB | |
| SCHEMBL21445353 | 0.84 | ALDH1A1 (0.51) | ALDH1A1IL1RNERAP2ERAP1CTSB | |
| SCHEMBL6963650 | 0.83 | ALDH1A1 (0.55) | ALDH1A1CTSBCTSKCTSLCTSS | |
| SCHEMBL22004939 | 0.83 | ALDH1A1 (0.50) | ALDH1A1IL1RNERAP2ERAP1CTSB | |
| SCHEMBL21274443 | 0.83 | ERAP2 (0.56) | ALDH1A1IL1RNERAP2ERAP1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |