Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 3/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22692566 | 0.86 | ALDH1A1 (0.58) | ALDH1A1MAPTHPGDHSD17B10L3MBTL1 | |
| SCHEMBL18510018 | 0.84 | ALDH1A1 (0.56) | ALDH1A1MAPTHPGDHSD17B10L3MBTL1 | |
| SCHEMBL6889409 | 0.84 | ALDH1A1 (0.56) | ALDH1A1MAPTHPGDHSD17B10L3MBTL1 | |
| SCHEMBL6982949 | 0.84 | ALDH1A1 (0.56) | ALDH1A1MAPTHPGDHSD17B10L3MBTL1 | |
| SCHEMBL12264780 | 0.84 | ALDH1A1 (0.56) | ALDH1A1MAPTHPGDHSD17B10L3MBTL1 | |
| SCHEMBL6963655 | 0.84 | ALDH1A1 (0.56) | ALDH1A1MAPTHPGDHSD17B10L3MBTL1 | |
| SCHEMBL6982935 | 0.84 | ALDH1A1 (0.56) | ALDH1A1MAPTHPGDHSD17B10L3MBTL1 | |
| SCHEMBL6959614 | 0.83 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1MAPK1SLC6A2SLC6A3 | |
| SCHEMBL21445354 | 0.83 | ALDH1A1 (0.55) | ALDH1A1MAPTHPGDHSD17B10L3MBTL1 | |
| SCHEMBL18430149 | 0.83 | ALDH1A1 (0.55) | ALDH1A1MAPTHPGDHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |