Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27834704 | 0.81 | GRIN2D (0.46) | CYP1A2CYP2C19CYP3A4CYP2C9HIF1A | |
| SCHEMBL3249422 | 0.74 | MTNR1A (0.53) | CYP1A2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7042682 | 0.73 | NFE2L2 (0.54) | NFE2L2MAOBRELA | |
| SCHEMBL9997630 | 0.72 | NFE2L2 (0.48) | CYP1A2CYP2C19CYP3A4CYP2C9HIF1A | |
| SCHEMBL9997628 | 0.72 | NFE2L2 (0.48) | CYP1A2CYP2C19CYP3A4CYP2C9HIF1A | |
| SCHEMBL87638 | 0.71 | TDP1 (0.48) | CYP1A2CYP2C9RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1781200 | 0.71 | MAPT (0.63) | CYP1A2NFE2L2MAOBRAB9ASMN1; SMN2 | |
| SCHEMBL29374751 | 0.71 | MAPT (0.63) | CYP1A2NFE2L2MAOBRAB9ASMN1; SMN2 | |
| SCHEMBL31464870 | 0.71 | MAPT (0.63) | CYP1A2NFE2L2MAOBRAB9ASMN1; SMN2 | |
| SCHEMBL1781201 | 0.71 | MAPT (0.63) | CYP1A2NFE2L2MAOBRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |