Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 5/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 8/20 | 0.49 |
| ▸ | DRD3 | P35462 | 8/20 | 0.49 |
| ▸ | DRD4 | P21917 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | VCP | P55072 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955497 | 0.93 | CCR3 (0.51) | CCR3HTR2ADRD2DRD3DRD4 | |
| SCHEMBL6951372 | 0.86 | MEN1 (0.48) | CCR3HTR2AMEN1CARM1PRMT6 | |
| SCHEMBL6959205 | 0.86 | CARM1 (0.47) | CCR3HTR2ACARM1PRMT6SLC6A4 | |
| SCHEMBL6953902 | 0.82 | DRD2 (0.44) | CCR3HTR2ADRD2DRD3DRD4 | |
| SCHEMBL6959344 | 0.82 | BCHE (0.46) | CCR3HTR2ADRD3MEN1CARM1 | |
| SCHEMBL6954494 | 0.81 | SLC6A4 (0.61) | SLC6A4 | |
| SCHEMBL6954897 | 0.81 | SLC6A4 (0.61) | SLC6A4 | |
| SCHEMBL6957708 | 0.81 | SLC6A4 (0.61) | SLC6A4 | |
| SCHEMBL6950244 | 0.80 | CARM1 (0.47) | CCR3HTR2ADRD4CARM1PRMT6 | |
| SCHEMBL6955452 | 0.80 | CARM1 (0.47) | CCR3HTR2AMEN1CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993458-B1 | 3-BENZYLPIPERIDINE | MERCK PATENT GMBH (DE) | 2003-04-09 | — | — | EP | disclosed |
| US-6333339-B1 | CENTRAL SYSTEM DISORDERS, SCHIZOPHRENIA AND COGNITION ACTIVATORS | MERCK PATENT GELLSCHAFT MIT BESCHRANKTER (DE) | 2001-12-25 | — | — | US | disclosed |
| EP-0993458-A1 | 3-BENZYLPIPERIDINE | MERCK PATENT GmbH (DE) | 2000-04-19 | — | — | EP | disclosed |
| WO-1998057953-A1 | 3-BENZYLPIPERIDINE | MERCK PATENT GMBH (DE) | 1998-12-23 | — | — | WO | disclosed |