Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.61 |
| ▸ | HTR1A | P08908 | 8/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6954897 | 1.00 | SLC6A4 (0.61) | SLC6A4HTR1AACHESLC6A2SLC6A3 | |
| SCHEMBL6954494 | 1.00 | SLC6A4 (0.61) | SLC6A4HTR1AACHESLC6A2SLC6A3 | |
| SCHEMBL6953432 | 0.93 | SLC6A4 (0.52) | SLC6A4HTR1AACHESLC6A2SLC6A3 | |
| SCHEMBL6958552 | 0.86 | MPO (0.61) | SLC6A4HTR1AKCNH2 | |
| SCHEMBL6951363 | 0.86 | HTR1A (0.55) | SLC6A4HTR1AHTR6KCNH2 | |
| SCHEMBL6952634 | 0.86 | MPO (0.61) | SLC6A4HTR1AKCNH2 | |
| SCHEMBL7358948 | 0.86 | HTR1A (0.54) | SLC6A4HTR1A | |
| SCHEMBL6957729 | 0.86 | MPO (0.61) | SLC6A4HTR1AKCNH2 | |
| SCHEMBL6950516 | 0.86 | HTR1A (0.56) | SLC6A4HTR1AHTR6 | |
| SCHEMBL7384064 | 0.84 | HTR1A (0.48) | SLC6A4HTR1AACHESLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993458-B1 | 3-BENZYLPIPERIDINE | MERCK PATENT GMBH (DE) | 2003-04-09 | — | — | EP | disclosed |
| US-6333339-B1 | CENTRAL SYSTEM DISORDERS, SCHIZOPHRENIA AND COGNITION ACTIVATORS | MERCK PATENT GELLSCHAFT MIT BESCHRANKTER (DE) | 2001-12-25 | — | — | US | disclosed |
| EP-0993458-A1 | 3-BENZYLPIPERIDINE | MERCK PATENT GmbH (DE) | 2000-04-19 | — | — | EP | disclosed |
| WO-1998057953-A1 | 3-BENZYLPIPERIDINE | MERCK PATENT GMBH (DE) | 1998-12-23 | — | — | WO | disclosed |