Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960215 | 0.85 | GAA (0.36) | GRM5KCNH2DHFRERN1MEN1 | |
| SCHEMBL6960207 | 0.76 | DHFR (0.38) | DHFRMEN1KMT2AELANELMNA | |
| SCHEMBL6964996 | 0.74 | PTGDR2 (0.38) | GRM5KCNH2DHFRERN1NPC1 | |
| SCHEMBL103255 | 0.70 | GRM5 (0.38) | GRM5KCNH2ELANE | |
| SCHEMBL102341 | 0.65 | GRM5 (0.39) | GRM5KCNH2TP53SMN1; SMN2 | |
| SCHEMBL7734764 | 0.64 | DHFR (0.40) | DHFRMEN1KMT2ALMNATP53 | |
| SCHEMBL102632 | 0.64 | GRM5 (0.40) | GRM5KCNH2ERN1NPC1RAB9A | |
| SCHEMBL103358 | 0.62 | GRM5 (0.42) | GRM5KCNH2NPC1RAB9AELANE | |
| SCHEMBL16004606 | 0.60 | GRM5 (0.57) | GRM5KCNH2 | |
| SCHEMBL30526535 | 0.60 | GRM5 (0.57) | GRM5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0785927-B1 | NOVEL BENZOXAZOLES | EURO CELTIQUE SA (LU) | 2003-08-27 | — | — | EP | claimed |