⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30718015 | 0.96 | CA12 (0.42) | — | |
| SCHEMBL1100115 | 0.92 | — | — | |
| SCHEMBL27874501 | 0.90 | CA12 (0.38) | — | |
| Fluoride SCHEMBL25262417 | 0.89 | CYP3A4 (0.37) | — | |
| SCHEMBL1100010 | 0.83 | MAP4K4 (0.48) | — | |
| Piperazine SCHEMBL7118889 | 0.83 | NISCH (0.34) | — | |
| SCHEMBL15650554 | 0.81 | CES2 (0.44) | — | |
| Pyrrolidine SCHEMBL7125470 | 0.79 | ALDH1A1 (0.36) | — | |
| SCHEMBL5508218 | 0.78 | — | — | |
| SCHEMBL1353866 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3151 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543430-A1 | SYNTHESIS OF TETRAHYDRONAPHTHALENOLS AND USES THEREOF | IO Therapeutics, Inc. (US) | 2025-04-30 | — | — | EP | claimed |
| CN-119707773-A | Preparation method and application of maleimide structure-containing compound | 中国农业大学 | 2025-03-28 | — | — | CN | claimed |
| CN-119552183-A | Narrow emission compound based on spirobifluorene and electroluminescent device prepared from narrow emission compound | 中国科学院宁波材料技术与工程研究所 | 2025-03-04 | — | — | CN | claimed |
| CN-119451672-A | Synthesis of tetrahydronaphthol and use thereof | IO治疗公司 | 2025-02-14 | — | — | CN | claimed |
| CN-118185245-B | Fiber reinforced polydicyclopentadiene composite material and preparation method thereof | 长春三友智造科技发展有限公司 | 2024-07-26 | — | — | CN | claimed |
| CN-118290310-A | Functional type Gemini air entraining agent and preparation method thereof | 江苏奥莱特新材料股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118271501-A | Maleimide heat-resistant flame-retardant modifier, heat-resistant flame-retardant ABS and preparation method thereof | 浙江烯苯醇新材料科技有限公司 | 2024-07-02 | — | — | CN | claimed |
| CN-118183708-A | Method for preparing fluorocarbon material by using fluorine-containing polymer | 重庆大学锂电及新材料遂宁研究院 | 2024-06-14 | — | — | CN | claimed |
| CN-118185245-A | Fiber reinforced polydicyclopentadiene composite material and preparation method thereof | 长春三友智造科技发展有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-118126030-A | Preparation method of pyrazoline-1, 3, 4-oxadiazole thioacetamide derivative and application of pyrazoline-1, 3, 4-oxadiazole thioacetamide derivative as pesticide | 贵州大学 | 2024-06-04 | — | — | CN | claimed |
| EP-0460639-B1 | Process for producing 3,5-difluoroaniline and derivative thereof | SDS BIOTECH CORP (JP) | 1995-12-27 | — | — | EP | claimed |
| EP-0497213-B1 | Process for producing 3,5-difluoroaniline | ISHIHARA SANGYO KAISHA (JP) | 1995-09-27 | — | — | EP | claimed |
| EP-0667337-A1 | Method for preparing fluoroanilines | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-16 | — | — | EP | claimed |
| EP-0562435-B1 | Process for the preparation of 3,5-difluoroaniline | HOECHST AG (DE) | 1995-06-07 | — | — | EP | claimed |
| US-5399767-A | Process for producing 3,5-difluoraniline | ISHIHARA SANGYO KAISHA LTD. (JP) | 1995-03-21 | — | — | US | claimed |
| US-5294742-A | Process for preparing 3,5-difluoroaniline | HOECHST ATKIENGESELLSCHAFT (DE) | 1994-03-15 | — | — | US | claimed |
| EP-0562435-A1 | Process for the preparation of 3,5-difluoroaniline | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | claimed |
| WO-1993014062-A1 | ANTHELMINTIC β-KETOAMIDES | THE UPJOHN COMPANY (US) | 1993-07-22 | — | — | WO | claimed |
| EP-0497213-A2 | Process for producing 3,5-difluoroaniline | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1992-08-05 | — | — | EP | claimed |
| EP-0460639-A1 | Process for producing 3,5-difluoroaniline and derivative thereof | SDS Biotech K.K. (JP) | 1991-12-11 | — | — | EP | claimed |