Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7083801 | 0.85 | POLB (0.47) | ALDH1A1HPGDSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6974959 | 0.85 | MAOA (0.36) | ALDH1A1HPGDSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL7084256 | 0.84 | SMN1; SMN2 (0.35) | SMN1; SMN2ALDH1A1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6967632 | 0.83 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1HPGDSLC6A4MAOA | |
| SCHEMBL6973932 | 0.83 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1HPGDSLC6A4MAOA | |
| SCHEMBL6968786 | 0.83 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1HPGDSLC6A4MAOA | |
| SCHEMBL7081061 | 0.82 | — | — | |
| SCHEMBL6972545 | 0.82 | POLB (0.32) | SLC6A4SLC6A2SLC6A3POLB | |
| SCHEMBL6974787 | 0.81 | SMN1; SMN2 (0.35) | SMN1; SMN2ALDH1A1HPGDSLC6A4MAOA | |
| SCHEMBL6974087 | 0.81 | SMN1; SMN2 (0.35) | SMN1; SMN2ALDH1A1HPGDSLC6A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |