Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960584 | 1.00 | GLO1 (0.46) | GLO1GAATDP1CYP1A2CYP2C9 | |
| SCHEMBL11547520 | 0.87 | GLO1 (0.57) | GLO1GAATDP1CYP1A2CYP2C9 | |
| SCHEMBL6954032 | 0.84 | MAPT (0.49) | GLO1GAATDP1MAPTHPGD | |
| SCHEMBL6954037 | 0.84 | MAPT (0.49) | GLO1GAATDP1MAPTHPGD | |
| SCHEMBL31634795 | 0.84 | MAPT (0.49) | GLO1GAATDP1MAPTHPGD | |
| SCHEMBL2424030 | 0.84 | GLO1 (0.65) | GLO1GAACYP1A2CYP2C9MAPT | |
| SCHEMBL15026370 | 0.84 | GLO1 (0.65) | GLO1GAACYP1A2CYP2C9MAPT | |
| SCHEMBL16285258 | 0.84 | HPGD (0.46) | GLO1GAATDP1CYP1A2CYP2C9 | |
| SCHEMBL2424031 | 0.84 | GLO1 (0.65) | GLO1GAACYP1A2CYP2C9MAPT | |
| SCHEMBL4776452 | 0.83 | CYP1A2 (0.45) | GAACYP1A2CYP2C9MAPTFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023267-B1 | PYRIDYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CERMOL SA (CH) | 2003-09-17 | — | — | EP | disclosed |
| US-6482841-B1 | Pyridyl compounds and pharmaceutical compositions containing them | CERMOL S.A. (CH) | 2002-11-19 | — | — | US | disclosed |
| EP-1023267-A1 | PYRIDYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CERMOL S.A. (CH) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999019302-A1 | PYRIDYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CERMOL S.A. (CH) | 1999-04-22 | — | — | WO | disclosed |
| US-4822798-A | Circulation-active 4-phenyl-6-substituted dihydropyrimidines | BAYER AKTIENGESELLSCHAFT (DE) | 1989-04-18 | — | — | US | disclosed |
| US-4596805-A | Pharmaceuticals | ORTHO PHARMACEUTICAL CORPORATION (US) | 1986-06-24 | — | — | US | disclosed |