Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6650903 | 0.92 | KDM4E (0.59) | PHGDHMAPTGAAKDM4ESMN1; SMN2 | |
| SCHEMBL6652797 | 0.90 | PHGDH (0.55) | PHGDHMAPTGAASMN1; SMN2CYP1A2 | |
| SCHEMBL6651512 | 0.89 | PHGDH (0.52) | PHGDHMAPTGAAALDH1A1CYP3A4 | |
| SCHEMBL6961537 | 0.89 | RBP4 (0.54) | MAPTGAAKDM4EALDH1A1POLB | |
| SCHEMBL6780801 | 0.88 | MAPT (0.47) | PHGDHMAPTGAAKDM4ESMN1; SMN2 | |
| SCHEMBL6960446 | 0.86 | NPC1 (0.60) | PHGDHMAPTGAAALDH1A1CYP1A2 | |
| SCHEMBL6650534 | 0.82 | PHGDH (0.59) | PHGDHMAPTGAAKDM4EALDH1A1 | |
| SCHEMBL6652246 | 0.82 | PHGDH (0.55) | PHGDHMAPTGAAKDM4ESMN1; SMN2 | |
| SCHEMBL6956179 | 0.81 | GAA (0.58) | MAPTGAAKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL6651279 | 0.80 | PHGDH (0.53) | PHGDHMAPTKDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6028195-A | AN ANTITUMOR AGENT WITH VERY LOW TOXICITIES | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-02-22 | — | — | US | disclosed |