Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6968501 | 0.77 | TP53 (0.32) | KDM4ETP53 | |
| SCHEMBL9959156 | 0.75 | TP53 (0.40) | KDM4ELMNATP53 | |
| SCHEMBL28280222 | 0.74 | POLB (0.38) | KDM4ELMNATP53 | |
| SCHEMBL30093980 | 0.68 | CA12 (0.43) | LMNA | |
| SCHEMBL25645264 | 0.68 | MAPT (0.43) | KDM4ELMNATP53 | |
| SCHEMBL403704 | 0.67 | CA12 (0.41) | KDM4E | |
| SCHEMBL2809402 | 0.67 | CYP3A4 (0.38) | KDM4ELMNA | |
| SCHEMBL6971381 | 0.65 | L3MBTL1 (0.48) | KDM4ELMNATP53 | |
| SCHEMBL14423764 | 0.65 | POLB (0.49) | KDM4ELMNA | |
| SCHEMBL5350341 | 0.65 | POLB (0.49) | KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | claimed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |