Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971384 | 0.82 | KDM4E (0.48) | L3MBTL1TDP1CTDSP1KDM4EMAPK1 | |
| SCHEMBL11359782 | 0.79 | TSHR (0.56) | L3MBTL1TDP1CTDSP1KDM4EMAPK1 | |
| SCHEMBL1041466 | 0.75 | NOTUM (0.53) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL2930813 | 0.74 | L3MBTL1 (0.44) | L3MBTL1TDP1CTDSP1KDM4EMAPK1 | |
| SCHEMBL14226107 | 0.71 | MAPT (0.36) | L3MBTL1TDP1CTDSP1KDM4EMAPK1 | |
| SCHEMBL13687490 | 0.71 | L3MBTL1 (0.39) | L3MBTL1TDP1CTDSP1KDM4EMAPK1 | |
| SCHEMBL13740220 | 0.69 | ALDH1A1 (0.55) | L3MBTL1TDP1CTDSP1KDM4EMAPK1 | |
| SCHEMBL17815671 | 0.67 | GAA (0.54) | L3MBTL1MAPK1ALDH1A1RAB9AGAA | |
| SCHEMBL1426662 | 0.66 | CYP1A2 (0.60) | L3MBTL1TDP1CTDSP1KDM4EMAPK1 | |
| SCHEMBL6960892 | 0.65 | KDM4E (0.32) | KDM4ELMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |