Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | ACACB | O00763 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | RBP4 | P02753 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22404274 | 0.97 | CA12 (0.55) | CA12CA14CA2CA1CA7 | |
| SCHEMBL22404234 | 0.94 | CA12 (0.58) | CA12CA14CA2CA1CA7 | |
| SCHEMBL22404306 | 0.87 | CA12 (0.51) | CA12CA14CA2CA1CA7 | |
| SCHEMBL24000169 | 0.86 | CA12 (0.50) | CA12CA14CA2CA1CA7 | |
| SCHEMBL23762384 | 0.85 | TGFBR1 (0.48) | CA12CA14CA2EPHX1 | |
| SCHEMBL22404333 | 0.79 | CA12 (0.49) | CA12CA14CA2CA1CA7 | |
| SCHEMBL60318 | 0.79 | EPHX1 (0.56) | CA12CA2CA1EPHX1ACACB | |
| SCHEMBL25223059 | 0.79 | CA12 (0.41) | CA12CA14CA2CA1CA7 | |
| SCHEMBL10209101 | 0.77 | EPHX1 (0.54) | CA12CA2CA1EPHX1ACACB | |
| SCHEMBL3207880 | 0.77 | KMT2A (0.49) | CA12CA2CA1EPHX1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882023-B1 | HISTAMINE H 3 RECEPTOR LIGANDS | BLACK JAMES FOUNDATION (GB) | 2003-06-04 | — | — | EP | disclosed |
| US-6080871-A | ANTIHISTAMINES | JAMES BLACK FOUNDATION LIMITED (GB) | 2000-06-27 | — | — | US | disclosed |