Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | CALML3 | P27482 | 7/20 | 0.43 |
| ▸ | MAOB | P27338 | 5/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SDHA | P31040 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6164483 | 1.00 | MAOA (0.52) | MAOAF10CALML3MAOBGRM2 | |
| SCHEMBL6161767 | 1.00 | MAOA (0.52) | MAOAF10CALML3MAOBGRM2 | |
| SCHEMBL5889283 | 1.00 | MAOA (0.52) | MAOAF10CALML3MAOBGRM2 | |
| SCHEMBL7928594 | 0.89 | CALML3 (0.55) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL6162646 | 0.85 | MAOA (0.46) | MAOAF10CALML3MAOBGRM2 | |
| SCHEMBL6160493 | 0.85 | MAOA (0.46) | MAOAF10CALML3MAOBGRM2 | |
| SCHEMBL6160497 | 0.85 | MAOA (0.46) | MAOAF10CALML3MAOBGRM2 | |
| SCHEMBL6703133 | 0.85 | MAOA (0.53) | MAOAF10CALML3MAOB | |
| SCHEMBL5739005 | 0.85 | MAOA (0.56) | MAOAF10CALML3MAOBLMNA | |
| SCHEMBL6160751 | 0.85 | MAOA (0.52) | MAOAF10CALML3MAOBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036074-B1 | S-OXIDE TETRAHYDROTHIOPYRAN PHENYLOXAZOLIDINONES | UPJOHN CO (US) | 2003-01-29 | — | — | EP | disclosed |
| EP-1254906-A1 | Tetrahydrothiopyran phenyloxazolidinone S,S-dioxides | PHARMACIA & UPJOHN COMPANY (US) | 2002-11-06 | — | — | EP | disclosed |
| US-6265178-B1 | Assay for determining oxazolidinone antibiotics having minimum monoamine oxidase inhibitory activity | PHARMACIA & UPJOHN COMPANY | 2001-07-24 | — | — | US | disclosed |