SCHEMBL5739005

SCHEMBL5739005

NCC1CN(c2ccc(C3CCC(O)CC3)c(F)c2)C(=O)O1

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.56
CALML3 P27482 7/20 0.47
F10 P00742 3/20 0.46
MAOB P27338 5/20 0.43
LMNA P02545 1/20 0.42
PTGS1 P23219 1/20 0.42
SDHA P31040 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5738485 0.88 MAOA (0.51) MAOACALML3F10MAOBLMNA
SCHEMBL6161576 0.87 MAOA (0.57) MAOACALML3F10MAOBLMNA
SCHEMBL6161567 0.87 MAOA (0.57) MAOACALML3F10MAOBLMNA
SCHEMBL6703133 0.87 MAOA (0.53) MAOACALML3F10MAOB
SCHEMBL5738647 0.86 MAOA (0.49) MAOACALML3F10MAOBLMNA
SCHEMBL4014717 0.86 MAOA (0.53) MAOACALML3F10MAOB
SCHEMBL6161767 0.85 MAOA (0.52) MAOACALML3F10MAOBLMNA
SCHEMBL5889283 0.85 MAOA (0.52) MAOACALML3F10MAOBLMNA
SCHEMBL6961483 0.85 MAOA (0.52) MAOACALML3F10MAOBLMNA
SCHEMBL6164483 0.85 MAOA (0.52) MAOACALML3F10MAOBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1660488-A1 NOVEL ANTIMICROBIAL ARYLOXAZOLIDINONE COMPOUNDS Warner-Lambert Company LLC (US) 2006-05-31 EP disclosed
US-20050065187-A1 Novel antimicrobial aryloxazolidinone compounds GORDEEV MIKHAIL FEDOROVICH (US) 2005-03-24 US disclosed
WO-2005019214-A1 NOVEL ANTIMICROBIAL ARYLOXAZOLIDINONE COMPOUNDS WARNER-LAMBERT COMPANY LLC (US) 2005-03-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050065187-A1 Novel antimicrobial aryloxazolidinone compounds XDH, NQO1, MPO MAOA 144/4885CALML3 4443/4885F10 4687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.