Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 5/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5628749 | 0.87 | ALDH1A1 (0.64) | NPC1RAB9ATDP1HTR1AADRA1D | |
| SCHEMBL19511901 | 0.84 | ERN1 (0.60) | NPC1RAB9ATDP1HTR1AADRA1D | |
| SCHEMBL10265524 | 0.84 | NPC1 (0.53) | NPC1RAB9ATDP1HTR1AADRA1D | |
| SCHEMBL3446415 | 0.84 | ALDH1A1 (0.54) | NPC1RAB9ATDP1HTR1AADRA1D | |
| SCHEMBL13006159 | 0.84 | NPC1 (0.53) | NPC1RAB9ATDP1HTR1AADRA1D | |
| SCHEMBL19512012 | 0.84 | NPC1 (0.45) | NPC1RAB9ATDP1HTR1AADRA1D | |
| SCHEMBL1050281 | 0.83 | CCNB2 (0.59) | NPC1RAB9ATDP1HTR1AADRA1D | |
| SCHEMBL1125006 | 0.82 | KDM4E (0.60) | NPC1RAB9AHTR1AADRA1DADRA1A | |
| SCHEMBL412487 | 0.82 | MAPT (0.54) | NPC1RAB9ATDP1HTR1AADRA1D | |
| SCHEMBL4294807 | 0.82 | CCNB2 (0.55) | TDP1HTR1AADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421529-A2 | SIDEROPHORE CONJUGATE IMMUNOGENIC COMPOSITIONS AND VACCINES | University of Florida Research Foundation, Inc. (US) | 2012-02-29 | — | — | EP | disclosed |
| WO-2010123845-A2 | SIDEROPHORE CONJUGATE IMMUNOGENIC COMPOSITIONS AND VACCINES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-10-28 | — | — | WO | disclosed |
| EP-0409164-B1 | Phenacylpyridiniothiocephalosporins | SHIONOGI & CO (JP) | 1996-06-05 | — | — | EP | disclosed |
| US-5134138-A | ANTIBIOTICS | SHIONOGI & CO., LTD. (JP) | 1992-07-28 | — | — | US | disclosed |
| EP-0409164-A2 | Phenacylpyridiniothiocephalosporins | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1991-01-23 | — | — | EP | disclosed |