Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 18/20 | 0.53 |
| ▸ | CTSB | P07858 | 3/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6961679 | 0.82 | CTSS (0.52) | CTSSCTSBCTSLCTSK | |
| SCHEMBL5357163 | 0.81 | CTSS (0.62) | CTSSCTSL | |
| SCHEMBL5366728 | 0.81 | CTSS (0.62) | CTSSCTSL | |
| SCHEMBL6836051 | 0.79 | CTSL (0.53) | CTSSCTSBCTSLCTSKHPGD | |
| SCHEMBL6965443 | 0.79 | CTSS (0.54) | CTSSCTSBCTSLHPGD | |
| SCHEMBL6063791 | 0.78 | CTSL (0.51) | CTSSCTSBCTSLHPGD | |
| SCHEMBL5361104 | 0.74 | CTSS (0.61) | CTSSCTSL | |
| SCHEMBL5359645 | 0.74 | CTSS (0.50) | CTSSCTSBCTSK | |
| SCHEMBL5361054 | 0.74 | CTSS (0.50) | CTSSCTSBCTSK | |
| SCHEMBL5365673 | 0.74 | CTSS (0.54) | CTSSCTSBCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218372-B1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMA (US) | 2003-07-02 | — | — | EP | disclosed |