Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.74 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.74 |
| ▸ | MAOA | P21397 | 1/20 | 0.74 |
| ▸ | CES2 | O00748 | 2/20 | 0.72 |
| ▸ | APP | P05067 | 1/20 | 0.71 |
| ▸ | ACHE | P22303 | 8/20 | 0.70 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.67 |
| ▸ | TUBB | P07437 | 1/20 | 0.67 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.67 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.67 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.67 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.67 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.67 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.67 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.67 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.67 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.67 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.67 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.67 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6961770 | 1.00 | MAOB (0.74) | MAOBABCB1MAOACES2APP | |
| SCHEMBL29038289 | 0.89 | CES2 (0.80) | MAOBMAOACES2ACHEMIF | |
| SCHEMBL29038294 | 0.89 | CES2 (0.80) | MAOBMAOACES2ACHEMIF | |
| SCHEMBL31501134 | 0.88 | MAOB (0.73) | MAOBABCB1MAOACES2APP | |
| SCHEMBL5690576 | 0.88 | MIF (0.69) | MAOBABCB1MAOAACHETUBB4A | |
| SCHEMBL5690658 | 0.87 | MAOB (0.64) | MAOBABCB1MAOACES2APP | |
| SCHEMBL8010257 | 0.87 | ACHE (0.74) | MAOBABCB1MAOAAPPACHE | |
| SCHEMBL27820343 | 0.87 | ACHE (0.74) | MAOBABCB1MAOAAPPACHE | |
| SCHEMBL30413650 | 0.87 | MAOB (0.84) | MAOBMAOACES2ACHEMIF | |
| SCHEMBL28927416 | 0.87 | MAOB (0.84) | MAOBMAOACES2ACHEMIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023063-B1 | INDENO[1,2-c], NAPHTHO[1,2-c]- AND BENZO[6,7]CYCLOHEPTA[1,2-c]PYRAZOLE DERIVATIVES | ABBOTT GMBH & CO KG (DE) | 2003-09-10 | — | — | EP | disclosed |