Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 11/20 | 0.47 |
| ▸ | MMP1 | P03956 | 9/20 | 0.47 |
| ▸ | MMP9 | P14780 | 8/20 | 0.47 |
| ▸ | MMP2 | P08253 | 8/20 | 0.47 |
| ▸ | MMP8 | P22894 | 6/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 5/20 | 0.43 |
| ▸ | MMP14 | P50281 | 5/20 | 0.43 |
| ▸ | MMP16 | P51512 | 5/20 | 0.43 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 6/20 | 0.42 |
| ▸ | PDE4A | P27815 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.41 |
| ▸ | SQSTM1 | Q13501 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6954815 | 0.85 | MMP1 (0.57) | MMP13MMP1MMP9MMP2MMP8 | |
| SCHEMBL6957207 | 0.81 | MMP1 (0.63) | MMP13MMP1MMP9MMP2MMP8 | |
| SCHEMBL27565303 | 0.78 | MMP1 (0.50) | MMP13MMP1MMP9MMP2MMP8 | |
| SCHEMBL6954028 | 0.72 | MMP1 (0.69) | MMP13MMP1MMP9MMP2MMP8 | |
| SCHEMBL6960996 | 0.71 | MMP1 (0.60) | MMP13MMP1MMP9MMP2MMP8 | |
| SCHEMBL6967193 | 0.71 | MMP1 (0.66) | MMP13MMP1MMP9MMP2MMP8 | |
| SCHEMBL6965530 | 0.69 | MMP1 (0.67) | MMP13MMP1MMP9MMP2MMP8 | |
| SCHEMBL6957161 | 0.69 | MMP1 (0.67) | MMP13MMP1MMP9MMP2MMP8 | |
| SCHEMBL6967896 | 0.69 | MMP1 (0.57) | MMP13MMP1MMP9MMP2MMP8 | |
| SCHEMBL6962839 | 0.69 | MMP1 (0.74) | MMP13MMP1MMP9MMP2MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977733-B1 | ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER PROD INC (US) | 2003-09-03 | — | — | EP | claimed |