Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.73 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | NPC1 | O15118 | 3/20 | 0.66 |
| ▸ | MAOA | P21397 | 1/20 | 0.66 |
| ▸ | MAOB | P27338 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | BCL6 | P41182 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.57 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.57 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6905303 | 0.85 | ALDH1A1 (0.71) | RAB9AALDH1A1ALOX12SMN1; SMN2MAPK1 | |
| SCHEMBL6952754 | 0.84 | ALDH1A1 (1.00) | RAB9AALDH1A1ALOX12SMN1; SMN2MAPK1 | |
| SCHEMBL29352156 | 0.84 | ALDH1A1 (1.00) | RAB9AALDH1A1ALOX12SMN1; SMN2MAPK1 | |
| SCHEMBL8891452 | 0.81 | RAB9A (0.57) | RAB9AALDH1A1ALOX12SMN1; SMN2MAPK1 | |
| SCHEMBL6524477 | 0.80 | RAB9A (1.00) | RAB9AALDH1A1ALOX12SMN1; SMN2MAPK1 | |
| SCHEMBL1520437 | 0.80 | RAB9A (1.00) | RAB9AALDH1A1SMN1; SMN2MAPK1NPC1 | |
| SCHEMBL12049597 | 0.79 | RAB9A (0.69) | RAB9AALDH1A1ALOX12SMN1; SMN2MAPK1 | |
| SCHEMBL6959672 | 0.79 | RAB9A (0.79) | RAB9AALDH1A1ALOX12SMN1; SMN2MAPK1 | |
| SCHEMBL1520344 | 0.78 | SMN1; SMN2 (0.71) | RAB9AALDH1A1ALOX12SMN1; SMN2MAPK1 | |
| SCHEMBL6960260 | 0.78 | RAB9A (0.60) | RAB9AALDH1A1ALOX12SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540143-B1 | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 2003-02-05 | — | — | EP | disclosed |
| US-5714503-A | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 1998-02-03 | — | — | US | disclosed |
| EP-0540143-A2 | Compounds and methods for inhibition of HIV and related viruses | Medivir Aktiebolag (SE) | 1993-05-05 | — | — | EP | disclosed |
| WO-1993003022-A1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1993-02-18 | — | — | WO | disclosed |