Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 16/20 | 0.54 |
| ▸ | MMP13 | P45452 | 16/20 | 0.54 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 4/20 | 0.46 |
| ▸ | MMP9 | P14780 | 4/20 | 0.46 |
| ▸ | MMP8 | P22894 | 3/20 | 0.46 |
| ▸ | MMP3 | P08254 | 3/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MMP7 | P09237 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960862 | 0.97 | MMP1 (0.54) | MMP1MMP13MEP1BMMP2MMP9 | |
| SCHEMBL6968116 | 0.95 | MMP1 (0.56) | MMP1MMP13MEP1BMMP2MMP9 | |
| SCHEMBL6965530 | 0.90 | MMP1 (0.67) | MMP1MMP13MMP2MMP9MMP8 | |
| SCHEMBL6968323 | 0.89 | MMP1 (0.68) | MMP1MMP13MMP2MMP9MMP8 | |
| SCHEMBL6950277 | 0.89 | MMP1 (0.66) | MMP1MMP13MEP1BMMP2MMP9 | |
| SCHEMBL6957161 | 0.88 | MMP1 (0.67) | MMP1MMP13MMP2MMP9MMP8 | |
| SCHEMBL6967193 | 0.85 | MMP1 (0.66) | MMP1MMP13MMP2MMP9MMP8 | |
| SCHEMBL6967655 | 0.80 | MMP13 (0.60) | MMP1MMP13MMP2MMP9MMP8 | |
| SCHEMBL7214282 | 0.79 | MMP1 (0.68) | MMP1MMP13MMP2MMP9MMP8 | |
| SCHEMBL6964498 | 0.78 | MMP1 (0.79) | MMP1MMP13MEP1BMMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977733-B1 | ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER PROD INC (US) | 2003-09-03 | — | — | EP | claimed |