Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 16/20 | 0.66 |
| ▸ | CTSS | P25774 | 14/20 | 0.66 |
| ▸ | CTSB | P07858 | 8/20 | 0.62 |
| ▸ | CTSK | P43235 | 6/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5362056 | 0.91 | CTSL (0.68) | CTSLCTSSCTSBCTSK | |
| SCHEMBL5359608 | 0.89 | CTSL (0.61) | CTSLCTSSCTSBCTSK | |
| SCHEMBL6967792 | 0.86 | CTSS (0.65) | CTSLCTSSCTSBCTSK | |
| SCHEMBL6970569 | 0.85 | CTSS (0.63) | CTSLCTSSCTSBCTSK | |
| SCHEMBL6974002 | 0.85 | CTSL (0.71) | CTSLCTSSCTSBCTSK | |
| SCHEMBL5365007 | 0.83 | CTSS (0.64) | CTSLCTSSCTSBCTSK | |
| SCHEMBL5365066 | 0.82 | CTSS (0.57) | CTSLCTSSCTSBCTSK | |
| SCHEMBL5365222 | 0.82 | CTSS (0.64) | CTSLCTSSCTSBCTSK | |
| SCHEMBL5365047 | 0.82 | CTSL (0.66) | CTSLCTSSCTSBCTSK | |
| SCHEMBL5357750 | 0.82 | CTSL (0.66) | CTSLCTSSCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218372-B1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMA (US) | 2003-07-02 | — | — | EP | disclosed |