Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | HTR1F | P30939 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966918 | 0.95 | SMN1; SMN2 (0.36) | SMN1; SMN2NPSR1MAPTHTR1AHTR1D | |
| SCHEMBL6963151 | 0.94 | HTR2A (0.35) | SMN1; SMN2NPSR1MAPTKCNH3KMT2A | |
| SCHEMBL6961241 | 0.90 | HTR2A (0.36) | SMN1; SMN2NPSR1MAPTKMT2AMEN1 | |
| SCHEMBL6954411 | 0.89 | SMN1; SMN2 (0.39) | SMN1; SMN2NPSR1MAPTHTR1AHTR1D | |
| SCHEMBL6970019 | 0.88 | SMN1; SMN2 (0.37) | SMN1; SMN2NPSR1MAPTKCNH3HTR1A | |
| SCHEMBL6957959 | 0.87 | SMN1; SMN2 (0.38) | SMN1; SMN2NPSR1MAPTHTR1AHTR1D | |
| SCHEMBL6958365 | 0.87 | MAPT (0.38) | SMN1; SMN2NPSR1MAPTKMT2AHTR2A | |
| SCHEMBL6963612 | 0.86 | KMT2A (0.35) | SMN1; SMN2NPSR1MAPTKCNH3HTR1A | |
| SCHEMBL6955513 | 0.85 | NPSR1 (0.36) | SMN1; SMN2NPSR1MAPTHTR1AHTR1D | |
| SCHEMBL6957761 | 0.85 | TP53 (0.40) | SMN1; SMN2NPSR1MAPTHTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | claimed |
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6352993-B1 | ANTIULCER AGENTS | YUHAN CORPORATION (KR) | 2002-03-05 | — | — | US | disclosed |