Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.35 |
| ▸ | GAK | O14976 | 1/20 | 0.35 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | YES1 | P07947 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.35 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.35 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.35 |
| ▸ | ABL2 | P42684 | 1/20 | 0.35 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.35 |
| ▸ | EPHA4 | P54764 | 1/20 | 0.35 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.35 |
| ▸ | ACVR2B | Q13705 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6957761 | 0.94 | TP53 (0.40) | SMN1; SMN2NPSR1KMT2AMAPTTP53 | |
| SCHEMBL6954411 | 0.94 | SMN1; SMN2 (0.39) | SMN1; SMN2NPSR1PDGFRBKMT2AMAPT | |
| SCHEMBL6961412 | 0.94 | SMN1; SMN2 (0.37) | SMN1; SMN2NPSR1KCNH3PDGFRBGAK | |
| SCHEMBL6961033 | 0.91 | SRD5A1 (0.36) | SMN1; SMN2ABL1LCKBCRSRC | |
| SCHEMBL6958474 | 0.91 | RORC (0.36) | SMN1; SMN2NPSR1MAPTTP53EGFR | |
| SCHEMBL6955513 | 0.90 | NPSR1 (0.36) | SMN1; SMN2NPSR1KMT2AMAPTTP53 | |
| SCHEMBL6966918 | 0.90 | SMN1; SMN2 (0.36) | SMN1; SMN2NPSR1KMT2AMAPTTP53 | |
| SCHEMBL6966508 | 0.90 | KMT2A (0.37) | SMN1; SMN2NPSR1KCNH3PDGFRBLCK | |
| SCHEMBL6961880 | 0.89 | KMT2A (0.38) | SMN1; SMN2NPSR1LCKKMT2AMAPT | |
| SCHEMBL6962636 | 0.89 | NR1D1 (0.34) | SMN1; SMN2NPSR1KMT2AMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6352993-B1 | ANTIULCER AGENTS | YUHAN CORPORATION (KR) | 2002-03-05 | — | — | US | disclosed |