Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11345241 | 0.89 | MEN1 (0.43) | MEN1KMT2AOPRD1BRD4HSD17B10 | |
| SCHEMBL696963 | 0.88 | MEN1 (0.41) | MEN1KMT2AOPRD1BRD4HSD17B10 | |
| SCHEMBL27733466 | 0.86 | OPRD1 (0.39) | MEN1KMT2AOPRD1OPRK1TDP1 | |
| SCHEMBL697554 | 0.86 | MEN1 (0.39) | MEN1KMT2AOPRD1BRD4HSD17B10 | |
| SCHEMBL696264 | 0.84 | TP53 (0.42) | MEN1KMT2AOPRD1HSD17B10OPRK1 | |
| SCHEMBL697954 | 0.81 | MEN1 (0.39) | MEN1KMT2AOPRD1BRD4HSD17B10 | |
| SCHEMBL697120 | 0.79 | MEN1 (0.44) | MEN1KMT2AOPRD1BRD4HSD17B10 | |
| SCHEMBL697949 | 0.78 | KMT2A (0.37) | MEN1KMT2AOPRD1HSD17B10OPRK1 | |
| SCHEMBL27733477 | 0.76 | OPRD1 (0.39) | MEN1KMT2AOPRD1OPRK1TDP1 | |
| SCHEMBL27733620 | 0.76 | OPRD1 (0.39) | MEN1KMT2AOPRD1OPRK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |