Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 13/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973240 | 0.95 | TRPV1 (0.60) | GPR52TRPV1HDAC3HDAC4HDAC1 | |
| SCHEMBL6971328 | 0.89 | GPR52 (0.68) | GPR52 | |
| SCHEMBL5847965 | 0.87 | GPR52 (0.56) | GPR52TRPV1HDAC3HDAC4HDAC1 | |
| SCHEMBL5847973 | 0.87 | GPR52 (0.56) | GPR52TRPV1HDAC3HDAC4HDAC1 | |
| SCHEMBL9113431 | 0.84 | GPR52 (0.53) | GPR52TRPV1HDAC3HDAC4HDAC1 | |
| SCHEMBL9113422 | 0.84 | GPR52 (0.53) | GPR52TRPV1HDAC3HDAC4HDAC1 | |
| SCHEMBL9113427 | 0.84 | GPR52 (0.53) | GPR52TRPV1HDAC3HDAC4HDAC1 | |
| SCHEMBL1150822 | 0.81 | TRPV1 (0.61) | GPR52TRPV1HDAC3HDAC4HDAC1 | |
| SCHEMBL1009881 | 0.81 | TRPV1 (0.61) | GPR52TRPV1HDAC3HDAC4HDAC1 | |
| SCHEMBL597782 | 0.80 | TRPV1 (0.64) | GPR52TRPV1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |