Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.60 |
| ▸ | GPR52 | Q9Y2T5 | 12/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963017 | 0.95 | GPR52 (0.54) | TRPV1GPR52MAPTRXFP1NPC1 | |
| SCHEMBL1009881 | 0.87 | TRPV1 (0.61) | TRPV1GPR52MAPTRXFP1HDAC3 | |
| SCHEMBL1150822 | 0.87 | TRPV1 (0.61) | TRPV1GPR52MAPTRXFP1HDAC3 | |
| SCHEMBL6971328 | 0.87 | GPR52 (0.68) | GPR52 | |
| SCHEMBL16288652 | 0.86 | TRPV1 (0.64) | TRPV1GPR52MAPTRXFP1HDAC3 | |
| SCHEMBL16289717 | 0.86 | TRPV1 (0.64) | TRPV1GPR52MAPTRXFP1HDAC3 | |
| SCHEMBL16289982 | 0.86 | TRPV1 (0.64) | TRPV1GPR52MAPTRXFP1HDAC3 | |
| SCHEMBL597782 | 0.86 | TRPV1 (0.64) | TRPV1GPR52MAPTRXFP1HDAC3 | |
| SCHEMBL16288651 | 0.86 | TRPV1 (0.64) | TRPV1GPR52MAPTRXFP1HDAC3 | |
| SCHEMBL16289718 | 0.86 | TRPV1 (0.64) | TRPV1GPR52MAPTRXFP1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |