Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.38 |
| ▸ | PPARA | Q07869 | 5/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955421 | 0.91 | FFAR1 (0.47) | FFAR1PPARAPPARG | |
| SCHEMBL6959497 | 0.85 | MAOB (0.55) | MAOBFFAR1PPARAMAOAPPARG | |
| SCHEMBL6964545 | 0.83 | PPARG (0.46) | FFAR1PPARAPPARG | |
| SCHEMBL6956226 | 0.78 | PPARG (0.52) | MAOBFFAR1PPARAPPARG | |
| SCHEMBL4239883 | 0.78 | MAOB (0.51) | MAOBFFAR1PPARA | |
| SCHEMBL6959041 | 0.78 | FFAR1 (0.47) | FFAR1PPARAPPARG | |
| SCHEMBL6966643 | 0.78 | FFAR1 (0.52) | FFAR1PPARAPPARG | |
| SCHEMBL6957024 | 0.77 | PPARG (0.49) | FFAR1PPARAPPARG | |
| SCHEMBL6961699 | 0.77 | PPARG (0.41) | FFAR1PPARAPPARG | |
| SCHEMBL6959897 | 0.77 | KDR (0.47) | MAOBFFAR1PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787725-B1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO (JP) | 2003-04-23 | — | — | EP | disclosed |
| CN-1071333-C | Quinoline derivative | NIPPON CHEMIPHAR CO (JP) | 2001-09-19 | — | — | CN | disclosed |
| CN-1170411-A | Quinoline derivative | NIPPON CHEMIPHAR CO (JP) | 1998-01-14 | — | — | CN | disclosed |
| EP-0787725-A1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-08-06 | — | — | EP | disclosed |