Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 10/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955421 | 0.92 | FFAR1 (0.47) | PPARGFFAR1PPARA | |
| SCHEMBL6961699 | 0.88 | PPARG (0.41) | PPARGCYP3A4RXRAFFAR1PPARA | |
| SCHEMBL6963053 | 0.83 | MAOB (0.43) | PPARGFFAR1PPARA | |
| SCHEMBL6961651 | 0.82 | PPARG (0.40) | PPARGFFAR1 | |
| SCHEMBL6956444 | 0.81 | PPARG (0.57) | PPARGCYP3A4RXRAFFAR1PPARA | |
| SCHEMBL29602962 | 0.80 | FFAR1 (0.59) | PPARGCYP3A4FFAR1PPARA | |
| SCHEMBL377641 | 0.80 | FFAR1 (0.59) | PPARGCYP3A4FFAR1PPARA | |
| SCHEMBL3969699 | 0.80 | FFAR1 (0.60) | PPARGCYP3A4RXRAFFAR1PPARA | |
| SCHEMBL6959041 | 0.80 | FFAR1 (0.47) | PPARGFFAR1PPARA | |
| SCHEMBL6966643 | 0.80 | FFAR1 (0.52) | PPARGCYP3A4RXRAFFAR1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787725-B1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO (JP) | 2003-04-23 | — | — | EP | disclosed |
| EP-0787725-A1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-08-06 | — | — | EP | disclosed |