Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3754568 | 0.74 | DPP4 (0.50) | DPP4F2HTR2ATAAR1ADRA2A | |
| SCHEMBL38740 | 0.74 | DPP4 (0.50) | DPP4F2HTR2ATAAR1ADRA2A | |
| SCHEMBL2374243 | 0.74 | DPP4 (0.50) | DPP4F2HTR2ATAAR1ADRA2A | |
| SCHEMBL1534125 | 0.74 | DPP4 (0.50) | DPP4F2HTR2ATAAR1ADRA2A | |
| SCHEMBL17286844 | 0.74 | DPP4 (0.50) | DPP4F2HTR2ATAAR1ADRA2A | |
| SCHEMBL255230 | 0.74 | DPP4 (0.50) | DPP4F2HTR2ATAAR1ADRA2A | |
| SCHEMBL1036921 | 0.74 | DPP4 (0.50) | DPP4F2HTR2ATAAR1ADRA2A | |
| SCHEMBL1683556 | 0.74 | DPP4 (0.50) | DPP4F2HTR2ATAAR1ADRA2A | |
| SCHEMBL27629498 | 0.74 | DPP4 (0.50) | DPP4F2HTR2ATAAR1ADRA2A | |
| SCHEMBL10402566 | 0.73 | UGT2B7 (0.47) | HTR2AHIF1AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |