SCHEMBL2374243

SCHEMBL2374243

C[CH]C(N)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.50
F2 P00734 1/20 0.50
ADRA2A P08913 1/20 0.44
ADRA2C P18825 1/20 0.44
LMNA P02545 1/20 0.44
HIF1A Q16665 1/20 0.44
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.43
TAAR1 Q96RJ0 3/20 0.41
HTR2A P28223 1/20 0.40
AOC3 Q16853 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23934880 0.80 DPP4 (0.46) DPP4F2ADRA2AADRA2CLMNA
SCHEMBL6944728 0.80 DPP4 (0.46) DPP4F2ADRA2AADRA2CLMNA
SCHEMBL11529524 0.75 ADRA2A (0.46) DPP4F2ADRA2AADRA2CLMNA
SCHEMBL10585298 0.75 ESR1 (0.48) LMNAHIF1AKDM4EALDH1A1TAAR1
SCHEMBL255230 0.74 DPP4 (0.50) DPP4F2ADRA2AADRA2CLMNA
SCHEMBL6963122 0.74 DPP4 (0.50) DPP4F2ADRA2AADRA2CLMNA
SCHEMBL1036921 0.74 DPP4 (0.50) DPP4F2ADRA2AADRA2CLMNA
SCHEMBL1534125 0.74 DPP4 (0.50) DPP4F2ADRA2AADRA2CLMNA
SCHEMBL38740 0.74 DPP4 (0.50) DPP4F2ADRA2AADRA2CLMNA
SCHEMBL17286844 0.74 DPP4 (0.50) DPP4F2ADRA2AADRA2CLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2978767-B1 DYEING METHOD USING A HAIR-DYEING PRECURSOR OBTAINED FROM IRIDOIDS, COMPOSITION, PRECURSOR AND DEVICE INCLUDING SAME OREAL (FR) 2018-10-03 EP disclosed
EP-2978767-A1 DYEING METHOD USING A HAIR-DYEING PRECURSOR OBTAINED FROM IRIDOIDS, COMPOSITION, PRECURSOR AND DEVICE INCLUDING SAME L'OREAL (FR) 2016-02-03 EP disclosed
EP-2978749-A1 OPTIONALLY PROTECTED IRIDOID-DERIVED COMPOUNDS, COMPOSITION INCLUDING SAME, USE AS A DYE FOR KERATIN FIBRES AND DEVICES L'Oréal (FR) 2016-02-03 EP disclosed
WO-2014154957-A1 DYEING METHOD USING A HAIR-DYEING PRECURSOR OBTAINED FROM IRIDOIDS, COMPOSITION, PRECURSOR AND DEVICE INCLUDING SAME L'OREAL (FR) 2014-10-02 WO disclosed
WO-2014155016-A1 OPTIONALLY PROTECTED IRIDOID-DERIVED COMPOUNDS, COMPOSITION INCLUDING SAME, USE AS A DYE FOR KERATIN FIBRES AND DEVICES L'OREAL (FR) 2014-10-02 WO disclosed
CN-101265273-B Phosphonopeptide and preparation method thereof UNIV BEIJING 2011-11-09 CN disclosed
WO-2011117553-A1 DYEING METHOD USING NON-GLYCOSYLATED IRIDOID DYES, DYEING COMPOSITION AND USE THEREOF L'OREAL (FR) 2011-09-29 WO disclosed
WO-2011117554-A1 DYEING METHOD USING A GLYCOSYLATED IRIDOID DERIVATIVE L'OREAL (FR) 2011-09-29 WO disclosed
US-20100098788-A1 Extracts of Curcuma and Methods of Use Thereof HERBALSCIENCE GROUP, LLC 2010-04-22 US disclosed
CN-101265273-A Phosphonopeptide and preparation method thereof UNIV BEIJING (CN) 2008-09-17 CN disclosed
EP-0318968-A2 Monoazo red dye compound having vinylsulfone type fiber reactive groups SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-06-07 EP disclosed
US-4837310-A LIGHTFAST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-06-06 US disclosed
EP-0284621-A1 NEW PSYCHOSTIMULANT AGENT. CHINOIN GYOGYSZER ES VEGYESZET (HU) 1988-10-05 EP disclosed
EP-0167858-B1 FIBER-REACTIVE DISAZO COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-09-07 EP disclosed
EP-0276686-A2 Anthraquinone compound and dyeing or printing method using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-08-03 EP disclosed
WO-1988002254-A1 NEW PSYCHOSTIMULANT AGENT Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. (HU) 1988-04-07 WO disclosed
US-4698421-A COLORFASTNESS; GOOD BUILD-UP; TRIAZINE DYES; CHEMICAL RESISTANCE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-10-06 US disclosed
US-4162314-A ANTIBIOTICS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1979-07-24 US disclosed
US-4153693-A 1,4-Dihydro-4-oxo-pyridylacetamido cephalosporins and their utilization as medicinal agents for combating bacterial infections MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1979-05-08 US disclosed
US-4031087-A INSECTICIDES SHELL OIL COMPANY (US) 1977-06-21 US disclosed