Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.59 |
| ▸ | RXRA | P19793 | 2/20 | 0.54 |
| ▸ | RARG | P13631 | 1/20 | 0.54 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | MPC2 | O95563 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964865 | 0.89 | PPARG (0.49) | PPARGRXRARARGPPARAALDH1A1 | |
| SCHEMBL6965562 | 0.86 | PPARG (0.74) | PPARGRXRARARGPPARAALDH1A1 | |
| SCHEMBL6184136 | 0.81 | PPARG (0.64) | PPARGRXRARARGPPARAFFAR1 | |
| SCHEMBL6965557 | 0.81 | PPARG (0.54) | PPARGRXRARARGPPARAFFAR1 | |
| SCHEMBL6963704 | 0.79 | PPARG (0.49) | PPARGRXRAAKT1PIK3CAPPARA | |
| SCHEMBL23578851 | 0.77 | PPARG (0.50) | PPARGRXRAAKT1PIK3CAPPARA | |
| SCHEMBL29764689 | 0.77 | PPARG (0.50) | PPARGRXRAAKT1PIK3CAPPARA | |
| SCHEMBL15348621 | 0.77 | PPARG (0.79) | PPARGRXRARARGPPARAFFAR1 | |
| SCHEMBL6964875 | 0.77 | FFAR1 (0.61) | PPARGRXRAPPARAFFAR1CYP3A4 | |
| SCHEMBL6955783 | 0.76 | FFAR1 (0.48) | PPARGRXRAPPARAFFAR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787725-B1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO (JP) | 2003-04-23 | — | — | EP | disclosed |
| EP-0787725-A1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-08-06 | — | — | EP | disclosed |