Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.74 |
| ▸ | RXRA | P19793 | 2/20 | 0.66 |
| ▸ | RARG | P13631 | 1/20 | 0.66 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963261 | 0.86 | PPARG (0.59) | PPARGRXRARARGPPARAALDH1A1 | |
| Rosiglitazone SCHEMBL11957687 | 0.85 | PPARG (1.00) | PPARGRXRARARGPPARAKDM4E | |
| Rosiglitazone SCHEMBL29530259 | 0.85 | PPARG (1.00) | PPARGRXRARARGPPARAKDM4E | |
| Rosiglitazone SCHEMBL2355017 | 0.85 | PPARG (1.00) | PPARGRXRARARGPPARAKDM4E | |
| Rosiglitazone SCHEMBL7052472 | 0.85 | PPARG (1.00) | PPARGRXRARARGPPARAKDM4E | |
| Rosiglitazone SCHEMBL5169 | 0.85 | PPARG (1.00) | PPARGRXRARARGPPARAKDM4E | |
| SCHEMBL6965557 | 0.85 | PPARG (0.54) | PPARGRXRARARGPPARAFFAR1 | |
| Rosiglitazone SCHEMBL1489117 | 0.84 | PPARG (0.98) | PPARGRXRARARGPPARAKDM4E | |
| Rosiglitazone SCHEMBL3377103 | 0.84 | PPARG (0.98) | PPARGRXRARARGPPARAKDM4E | |
| Rosiglitazone SCHEMBL5468691 | 0.84 | PPARG (0.98) | PPARGRXRARARGPPARAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787725-B1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO (JP) | 2003-04-23 | — | — | EP | disclosed |
| EP-0787725-A1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-08-06 | — | — | EP | disclosed |