Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.49 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RARG | P13631 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963261 | 0.89 | PPARG (0.59) | PPARGRXRARARGFFAR1ALDH1A1 | |
| SCHEMBL6963704 | 0.84 | PPARG (0.49) | PPARGRXRAFFAR1ALDH1A1NPSR1 | |
| SCHEMBL6964875 | 0.82 | FFAR1 (0.61) | PPARGRXRAFFAR1CYP3A4PPARA | |
| SCHEMBL23578851 | 0.80 | PPARG (0.50) | PPARGRXRAFFAR1ALDH1A1NPSR1 | |
| SCHEMBL29764689 | 0.80 | PPARG (0.50) | PPARGRXRAFFAR1ALDH1A1NPSR1 | |
| SCHEMBL6954013 | 0.78 | MAOA (0.48) | PPARGRXRAFFAR1ALDH1A1NPSR1 | |
| SCHEMBL6964870 | 0.78 | ALDH1A1 (0.44) | PPARGRXRAFFAR1ALDH1A1NPSR1 | |
| SCHEMBL29602962 | 0.78 | FFAR1 (0.59) | PPARGFFAR1CYP3A4PPARA | |
| SCHEMBL377641 | 0.78 | FFAR1 (0.59) | PPARGFFAR1CYP3A4PPARA | |
| SCHEMBL6958784 | 0.77 | FFAR1 (0.58) | PPARGRXRAFFAR1CYP3A4PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787725-B1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO (JP) | 2003-04-23 | — | — | EP | disclosed |
| EP-0787725-A1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-08-06 | — | — | EP | disclosed |