Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1149407 | 0.77 | TSHR (0.31) | — | |
| SCHEMBL21359729 | 0.73 | ALDH1A1 (0.33) | — | |
| SCHEMBL9211200 | 0.73 | FAAH (0.33) | FAAHMGLL | |
| SCHEMBL61668 | 0.71 | TSHR (0.33) | FAAHMGLL | |
| SCHEMBL6591774 | 0.70 | — | — | |
| SCHEMBL9207844 | 0.69 | TSHR (0.34) | FAAHMGLL | |
| SCHEMBL9205178 | 0.69 | TSHR (0.34) | FAAHMGLL | |
| SCHEMBL9204392 | 0.69 | TSHR (0.34) | FAAHMGLL | |
| SCHEMBL62014 | 0.69 | TSHR (0.34) | FAAHMGLL | |
| SCHEMBL9214217 | 0.69 | TSHR (0.34) | FAAHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0848004-B1 | PYRROLIDINE DERIVATIVES HAVING PHOSPHOLIPASE A2 INHIBITORY ACTIVITY | SHIONOGI & CO (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-5955616-A | PROSTAGLANDIN INHIBITORS | SHIONOGI & CO., LTD. (JP) | 1999-09-21 | — | — | US | disclosed |
| EP-0848004-A1 | PYRROLIDINE DERIVATIVES HAVING PHOSPHOLIPASE A2 INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 1998-06-17 | — | — | EP | disclosed |