Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10236319 | 0.77 | FAAH (0.40) | FAAHELANESMN1; SMN2USP2 | |
| SCHEMBL3086177 | 0.77 | FAAH (0.40) | FAAHELANESMN1; SMN2USP2 | |
| SCHEMBL3231153 | 0.77 | ALDH1A1 (0.47) | FAAHELANELMNATP53KMT2A | |
| SCHEMBL14060432 | 0.74 | FAAH (0.38) | FAAHELANESMN1; SMN2USP2 | |
| SCHEMBL28915641 | 0.74 | FAAH (0.41) | FAAHELANESMN1; SMN2PTGDR2USP2 | |
| SCHEMBL10279632 | 0.74 | FAAH (0.41) | FAAHELANESMN1; SMN2PTGDR2USP2 | |
| SCHEMBL6956991 | 0.73 | CYP1A2 (0.43) | FAAHELANEPTGDR2LMNA | |
| SCHEMBL30676944 | 0.72 | ALDH1A1 (0.40) | FAAHELANESMN1; SMN2LMNATP53 | |
| SCHEMBL30676992 | 0.72 | ALDH1A1 (0.40) | FAAHELANELMNATP53KMT2A | |
| SCHEMBL2955684 | 0.71 | FAAH (0.41) | FAAHELANESMN1; SMN2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |