Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL696365 | 1.00 | KDM4E (0.39) | KDM4ECA9CYP2D6CYP2C19CASP3 | |
| SCHEMBL695940 | 1.00 | KDM4E (0.39) | KDM4ECA9CYP2D6CYP2C19CASP3 | |
| SCHEMBL696851 | 0.78 | MAPT (0.36) | LMNAMAPT | |
| SCHEMBL695709 | 0.78 | MAPT (0.36) | LMNAMAPT | |
| SCHEMBL695710 | 0.78 | MAPT (0.36) | LMNAMAPT | |
| SCHEMBL1517603 | 0.77 | — | — | |
| SCHEMBL696542 | 0.74 | LMNA (0.30) | LMNA | |
| SCHEMBL696543 | 0.74 | LMNA (0.30) | LMNA | |
| SCHEMBL696828 | 0.74 | LMNA (0.30) | LMNA | |
| SCHEMBL7283216 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9770027-B2 | Heteroarylpiperidine and -piperazine derivatives as fungicides | BAYER CROPSCIENCE AG (DE) | 2017-09-26 | — | — | US | disclosed |
| US-20150351403-A1 | Heteroarylpiperidine and -piperazine derivatives as fungicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2015-12-10 | — | — | US | disclosed |
| US-9150565-B2 | Heteroarylpiperidine and -piperazine derivatives as fungicides | BAYER CROPSCIENCE AG (DE) | 2015-10-06 | — | — | US | disclosed |
| US-20140206646-A1 | Heteroarylpiperidine and -piperazine derivatives as fungicides | BAYER CROPSCIENCE AG (DE) | 2014-07-24 | — | — | US | disclosed |
| US-8759527-B2 | Heteroarylpiperidine and -piperazine derivatives as fungicides | BAYER CROPSCIENCE AG (DE) | 2014-06-24 | — | — | US | disclosed |
| EP-2423210-A1 | Heteroarylpiperidine and heteroarylpiperazine derivatives as fungicides | Bayer CropScience AG (DE) | 2012-02-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150351403-A1 | Heteroarylpiperidine and -piperazine derivatives as fungicides | CYP1A1, PRXL2A, CYP1A2 | KDM4E 1830/4885CA9 3170/4885CYP2D6 68/4885 |
| US-20140206646-A1 | Heteroarylpiperidine and -piperazine derivatives as fungicides | CYP1A1, PRXL2A, CYP1A2 | KDM4E 1830/4885CA9 3170/4885CYP2D6 68/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.