Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 5/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | CALML3 | P27482 | 1/20 | 0.41 |
| ▸ | SDHA | P31040 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963692 | 1.00 | F10 (0.43) | F10RORCMAOBMAOALMNA | |
| SCHEMBL6956015 | 0.88 | MAOB (0.44) | F10MAOBMAOACALML3 | |
| SCHEMBL6972550 | 0.87 | GRM2 (0.38) | F10MAOBMAOALMNAPTGS1 | |
| SCHEMBL7597985 | 0.84 | GRM2 (0.38) | MAOBMAOA | |
| SCHEMBL6964120 | 0.82 | MAOA (0.52) | F10MAOBMAOALMNAPTGS1 | |
| SCHEMBL27578381 | 0.82 | MAOA (0.52) | F10MAOBMAOALMNAPTGS1 | |
| SCHEMBL6296097 | 0.82 | TMEM97 (0.56) | — | |
| SCHEMBL5725604 | 0.82 | MAOB (0.56) | F10MAOBMAOALMNAPTGS1 | |
| SCHEMBL6296095 | 0.82 | TMEM97 (0.56) | — | |
| SCHEMBL6291704 | 0.82 | TMEM97 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181288-B1 | BICYCLIC OXAZOLIDINONES AS ANTIBACTERIAL AGENT | UPJOHN CO (US) | 2003-07-30 | — | — | EP | disclosed |
| US-6387896-B1 | GRAMNEGATIVE, GRAMPOSITVE BACTERIA | PHARMACIA & UPJOHN CO. | 2002-05-14 | — | — | US | disclosed |