Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.30 |
| ▸ | ADH1B | P00325 | 1/20 | 0.30 |
| ▸ | ADH1C | P00326 | 1/20 | 0.30 |
| ▸ | ADH1A | P07327 | 1/20 | 0.30 |
| ▸ | ADH4 | P08319 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971461 | 0.98 | SHBG (0.35) | SHBGSMN1; SMN2 | |
| SCHEMBL6968166 | 0.90 | CACNA2D1 (0.30) | — | |
| SCHEMBL6971572 | 0.84 | SHBG (0.46) | SHBGEPHX1KDM4EALDH1A1 | |
| SCHEMBL22244734 | 0.83 | ADH1A (0.42) | SHBGSMN1; SMN2EPHX1ADH1BADH1C | |
| SCHEMBL6968801 | 0.82 | SHBG (0.43) | SHBGEPHX1KDM4E | |
| SCHEMBL6965872 | 0.81 | SHBG (0.36) | SHBGSMN1; SMN2EPHX1 | |
| SCHEMBL6963958 | 0.81 | SHBG (0.34) | SHBGSMN1; SMN2EPHX1KDM4EALDH1A1 | |
| SCHEMBL6970474 | 0.79 | SHBG (0.33) | SHBGSMN1; SMN2 | |
| SCHEMBL25764901 | 0.77 | SHBG (0.41) | SHBGSMN1; SMN2PKMCTDSP1EPHX1 | |
| SCHEMBL13080892 | 0.76 | SHBG (0.41) | SHBGSMN1; SMN2PKMCTDSP1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0870765-B1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARM CO LTD (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-5981557-A | HAVING IMPROVING EFFECTS ON THE DYSMOTILITY IN THE GASTROINTESTINAL TRACT | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0870765-A1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |