Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963747 | 1.00 | HIF1A (0.37) | HIF1ATSHRKDM4EALDH1A1MAPT | |
| SCHEMBL7875493 | 0.84 | LMNA (0.35) | TSHRMAPT | |
| SCHEMBL7875492 | 0.84 | LMNA (0.35) | TSHRMAPT | |
| SCHEMBL7457347 | 0.81 | TSHR (0.50) | HIF1ATSHRKDM4EMAPT | |
| SCHEMBL27446293 | 0.81 | TSHR (0.50) | HIF1ATSHRKDM4EMAPT | |
| SCHEMBL6965419 | 0.80 | HIF1A (0.39) | HIF1ATSHRALDH1A1MAPT | |
| SCHEMBL6965418 | 0.80 | HIF1A (0.39) | HIF1ATSHRALDH1A1MAPT | |
| SCHEMBL28845729 | 0.80 | TDP1 (0.52) | KDM4EALDH1A1MAPT | |
| SCHEMBL9043211 | 0.80 | CA1 (0.52) | HIF1AALDH1A1MAPT | |
| SCHEMBL9659551 | 0.80 | CA1 (0.52) | HIF1AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |