SCHEMBL6963757

SCHEMBL6963757

Cc1nc(NCC(C)C)nc(N2CCc3ccccc3C2C)c1C

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HHAT Q5VTY9 3/20 0.38
HRH4 Q9H3N8 3/20 0.34
ESR1 P03372 4/20 0.33
CYP2D6 P10635 1/20 0.33
IDH1 O75874 1/20 0.33
SPR P35270 3/20 0.33
OPRM1 P35372 1/20 0.32
DRD1 P21728 1/20 0.32
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6969064 0.85 NPY5R (0.34) HRH4SPRDRD1
Hydrochloric Acid SCHEMBL6957536 0.83 PRCP (0.36)
SCHEMBL7688194 0.83 KCNH3 (0.39) OPRM1
Hydrochloric Acid SCHEMBL6965931 0.83 HRH4 (0.35) HRH4CYP2D6OPRM1
Hydrochloric Acid SCHEMBL6962293 0.82 HRH4 (0.44) HRH4ESR1ESR2
Hydrochloric Acid SCHEMBL6966669 0.82 KCNH3 (0.38) OPRM1
SCHEMBL6995590 0.81 ALDH1A1 (0.38)
SCHEMBL6990113 0.81 ALDH1A1 (0.38)
SCHEMBL6996524 0.81 ALDH1A1 (0.38)
Hydrochloric Acid SCHEMBL6962278 0.81 PLK1 (0.42) IDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1015444-B1 PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORP LTD (KR) 2003-05-28 EP disclosed
US-6352993-B1 ANTIULCER AGENTS YUHAN CORPORATION (KR) 2002-03-05 US disclosed