Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 17/20 | 0.72 |
| ▸ | MMP1 | P03956 | 8/20 | 0.72 |
| ▸ | MMP2 | P08253 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963754 | 1.00 | MMP3 (0.72) | MMP3MMP1MMP2CA1CA2 | |
| SCHEMBL6958038 | 0.84 | MMP3 (1.00) | MMP3MMP1MMP2 | |
| SCHEMBL6966746 | 0.83 | MMP3 (0.59) | MMP3MMP1MMP2 | |
| SCHEMBL6966752 | 0.83 | MMP3 (0.59) | MMP3MMP1MMP2 | |
| SCHEMBL8709654 | 0.80 | MMP3 (0.60) | MMP3MMP1MMP2CA1CA2 | |
| SCHEMBL6961135 | 0.79 | MMP3 (0.77) | MMP3MMP1MMP2CA1CA2 | |
| SCHEMBL6952470 | 0.78 | MMP3 (0.72) | MMP3MMP1MMP2 | |
| SCHEMBL8150208 | 0.74 | MMP3 (0.71) | MMP3MMP1MMP2CA1CA2 | |
| SCHEMBL10136037 | 0.71 | MMP3 (1.00) | MMP3MMP1MMP2 | |
| SCHEMBL5443538 | 0.71 | MMP3 (1.00) | MMP3MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021424-B1 | THIADIAZOLE AMIDE MMP INHIBITORS | UPJOHN CO (US) | 2003-02-26 | — | — | EP | disclosed |
| US-5830869-A | METALLOPROTEASE INHIBITOR | PHARMACIA & UPJOHN COMPANY | 1998-11-03 | — | — | US | disclosed |