Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10974071 | 0.96 | ALDH1A1 (0.69) | ALDH1A1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL30106089 | 0.85 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL16378590 | 0.82 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL9530535 | 0.82 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL4399146 | 0.82 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL10559488 | 0.82 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL15362563 | 0.80 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL11228856 | 0.79 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL2453384 | 0.77 | — | — | |
| SCHEMBL30106104 | 0.75 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2ATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0768879-B1 | THIADIAZOLE COMPOUNDS AS D3 DOPAMINE RECEPTOR LIGANDS | BASF AG (DE) | 2003-03-19 | — | — | EP | disclosed |
| US-5958923-A | TREATMENT OF NERVOUS SYSTEM DISORDERS | BASF AKTIENGESELLSCHAFT (DE) | 1999-09-28 | — | — | US | disclosed |
| EP-0768879-A1 | USE OF THIAZOLE AND THIADIAZOLE COMPOUNDS AS D3 DOPAMINE RECEPTOR LIGANDS | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-23 | — | — | EP | disclosed |
| WO-1996002249-A1 | USE OF THIAZOLE AND THIADIAZOLE COMPOUNDS AS D3 DOPAMINE RECEPTOR LIGANDS | BASF AKTIENGESELLSCHAFT (DE) | 1996-02-01 | — | — | WO | disclosed |